After two poor losses in the United States that saw no goals scored and six goals surrendered, manager Frank Lampard warned of another Premier League relegation struggle.
Last season, Everton only won their last game to guarantee their place in the Premier League.
In the first 11 minutes, Vitalii Mykolenko and Tom Davies scored for the Toffees.
Championship Gary Madine gave Blackpool a point just before halftime.
After the interval, former Tottenham and England midfielder Alli, 26, made it 3-1 before Callum Connolly scored to give the Seasiders a goal back. In minute 63, Alli’s close-range second goal ended the game.
The team’s first game of their US tour ended in a 2-0 loss to Arsenal, and three days later, Minnesota United of Major League Soccer suffered a 4-0 defeat.
This past weekend, a small group of supporters demonstrated in front of Goodison Park to draw attention to what they believe to be the “mismanagement” of the team by owner Farhad Moshiri.
Recent takeover talks stopped, and Moshiri reiterated the club was not up for sale.
Meanwhile, in the last match of their preseason tour of Portugal, freshly promoted Fulham defeated GD Estoril Praia 3-1.
Before the new acquisition Joao Palhinha scored his first goal for Marco Silva’s team; Aleksandar Mitrovic, who established a Championship record with 43 goals last season, scored twice off of headers.