After being given a chance to bat in Leicester’s humid conditions, England amassed a score of 371-7, their fifth-highest ODI total and only seven runs shy of their record against Pakistan in 2016.
In her 119 off 107 balls, Beaumont hammered 19 fours and a six, sharing a century-opening partnership with Emma Lamb, who scored 65.
After accomplishing this feat for the first time in the second ODI, England’s top four scored more than 50 runs again, thanks to Sophia Dunkley’s 51-run follow-up to her first ODI century and skipper Heather Knight’s 49-ball 63.
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The visitors were defeated 109-4 after Laura Wolvaardt responded with an impressive 56 before Charlie Dean withdrew her for the third time in the match.
The chase was given life by Chloe Tryon (70 off 57 balls) and Marizanne Kapp (62 off 54), who put on 110 for the fifth wicket. However, after both fell inside a five-over span, England could get rid of the rest of the South African team and bowl them out for 262.
Spinners Dean and Lamb ended with 3-42, while Alice Davidson-Richards finished with 3-35.
After winning the ODI series 3-0, the victory gives England an 8-2 advantage in the multi-format series.
Each game in the three-match Twenty20 series, which begins on Thursday at 19:00 BST in Chelmsford, is worth two points.
