The first batch of the Russian-made Sputnik V Covid-19 vaccine is expected to arrive in India on Saturday as Covid-19 cases and deaths have risen in the country.
Sputnik V has been jointly developed by the Gamaleya National Research Center for Epidemiology and Microbiology and RDIF. In India, the vaccine is being marketed by Hyderabad-based Dr. Reddy’s Laboratories. RDIF partnered with Dr. Reddy’s to conduct clinical trials in the country in September 2020. Reddy’s applied for government approval for the vaccine to be used in India.
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How much does Sputnik V cost?
The cost of one dose of the vaccine for international markets is less than $ 10 (Sputnik V is a two-dose vaccine). However, India has yet to negotiate prices.
How does Sputnik V work?
The Gam-COVID-Vac, called Sputnik V, is a two-part vaccine that includes two adenovirus vectors: recombinant human adenovirus type 26 (rAd26-S) and recombinant human adenovirus type 5 (rAd5-S). These vectors have been modified to express the SARS-CoV-2 spike protein, which the virus uses to enter human cells.
Adenoviruses are also weakened so that they cannot replicate in human cells and cannot cause disease.
In the trial, participants received a dose of rAd26-S, followed by a booster dose of rAd5-S 21 days later. The researchers explained that using a different adenovirus vector for the booster vaccine can help create a more powerful immune response, compared to using the same vector twice, as it minimizes the risk of the immune system developing resistance. to the initial vector.
Sputnik V dosage
Sputnik V is a two-dose vaccine. The vaccine is administered separately in a first and second dose, 21 days apart. Maximum immunity develops between day 28 and day 42. Sputnik V is said to be easy to transport, needs a storage temperature of 2-8 degrees C. That means it can be stored in conventional refrigerators and does not require additional cold. chain infrastructure.
Sputnik V efficiency
Sputnik V is reportedly 91.6 percent effective against coronavirus, which is among the best-performing vaccines, along with Pfizer / BioNTech and Moderna injections that also reported more than 90% efficacy. This is significant as both Covishield and Covaxin showed the efficacy of around 81 percent in the trials.
“Sputnik V is one of the three vaccines in the world with the efficacy of more than 90%. The efficacy of the vaccine is confirmed by 91.6% according to the analysis of data from 19,866 volunteers, who received both the first and second Final checkpoint doses of Sputnik V vaccine or placebo in 78 confirmed COVID-19 cases, based on information available on the official vaccine website.
Sputnik V side effects
There are no concerns that the Sputnik V vaccine could potentially cause harm to a person’s health. Investigators have reported rare serious adverse events. The number of cases that required hospital admission was also negligible.
So far, four deaths have been reported in the trial, none of which were said to be related to the vaccine. Most of the reported adverse effects were mild, including flu-like symptoms, injection site pain, and weakness or low energy.
Sputnik V has a number of key advantages, including the fact that there are no strong allergies caused by Sputnik V.
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