United will reportedly pay an initial sum of £80.75 million, with a further £4.25 million in add-ons.
Within 48 hours, the 22-year-old is expected to go to Manchester for medical treatment.
Harry Maguire and Antony would tie for the second-most expensive acquisition at Manchester United, behind Paul Pogba’s £89 million price tag, which still stands as the club record.
Antony, who joined the Dutch team from Sao Paulo in 2020 and played under current United manager Erik ten Hag, scored 25 goals and contributed 22 assists in 82 games for Ajax.
He has scored twice in nine matches since making his Brazil debut in October 2021.
The joint-fourth most expensive acquisition in Premier League history was Antony, who assisted on seven goals in his 11 Champions League outings for Ajax.
The only transfers that would be more expensive are Pogba’s to United, Romelu Lukaku to Chelsea, and Jack Grealish to Manchester City.
On Thursday, September 1, United’s next Premier League game is against Leicester City, but Antony would first need to get a work visa.
After the arrivals of his old Ajax teammate, defender Lisandro Martinez, midfielder Casemiro from Real Madrid, full-back Tyrell Malacia from Feyenoord, and playmaker Christian Eriksen on a free transfer, the attacker would become United’s sixth acquisition of the summer.
There is speculation over Cristiano Ronaldo’s future at the club due to worries that the 37-year-attitude old’s is depleting team spirit.